Name: Dna Methylation Microarrays: Experimental Design and Statistical Analysis (en Inglés)
Price: 79.43 USD
Availability: InStock
Author: Sun-Chong Wang; Art Petronis
ISBN: 9780367387402

portada Dna Methylation Microarrays: Experimental Design and Statistical Analysis (en Inglés)

Formato

Libro Físico

Editorial

Crc Pr Inc

Autor

Sun-Chong Wang; Art Petronis

Idioma

Inglés

N° páginas

256

Encuadernación

Tapa Blanda

ISBN13

9780367387402

N° edición

Dna Methylation Microarrays: Experimental Design and Statistical Analysis (en Inglés)

Sun-Chong Wang; Art Petronis (Autor) · Crc Pr Inc · Tapa Blanda

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$ 79.43

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Origen: Estados Unidos (Costos de importación incluídos en el precio)

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Reseña del libro "Dna Methylation Microarrays: Experimental Design and Statistical Analysis (en Inglés)"

Providing an interface between dry-bench bioinformaticians and wet-lab biologists, DNA Methylation Microarrays: Experimental Design and Statistical Analysis presents the statistical methods and tools to analyze high-throughput epigenomic data, in particular, DNA methylation microarray data. Since these microarrays share the same underlying principles as gene expression microarrays, many of the analyses in the text also apply to microarray-based gene expression and histone modification (ChIP-on-chip) studies.After introducing basic statistics, the book describes wet-bench technologies that produce the data for analysis and explains how to preprocess the data to remove systematic artifacts resulting from measurement imperfections. It then explores differential methylation and genomic tiling arrays. Focusing on exploratory data analysis, the next several chapters show how cluster and network analyses can link the functions and roles of unannotated DNA elements with known ones. The book concludes by surveying the open source software (R and Bioconductor), public databases, and other online resources available for microarray research. Requiring only limited knowledge of statistics and programming, this book helps readers gain a solid understanding of the methodological foundations of DNA microarray analysis.